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Product Overview
REJURAN S is a high-viscosity polynucleotide (PN) injectable medical device manufactured by PharmaResearch Co., Ltd. in South Korea. Formulated with purified, salmon-derived sodium polynucleotide at 20 mg/mL, REJURAN S is distinguished by its thicker consistency and lower spreadability compared with standard REJURAN.
Commonly associated with targeted treatment of depressed skin areas and acne scars, REJURAN S is supplied in a 1 mL prefilled syringe. Its manufacturer-stated intended purpose is the temporary improvement of facial wrinkles. The product is intended for use by qualified healthcare professionals in accordance with applicable local regulations and approved labeling.
Key Features
- 20 mg/mL Polynucleotide (PN): Contains purified salmon-derived sodium polynucleotide, a DNA-based polymer used in tissue-restoration medical devices.
- High-Viscosity Formulation: Features higher viscosity and lower spreadability than standard REJURAN, providing a more localized formulation characteristic.
- DOT™ Technology: Incorporates PharmaResearch's proprietary DNA Optimizing Technology, developed for the processing and purification of salmon-derived polynucleotides.
- Single-Syringe Packaging: Supplied as one 1 mL prefilled syringe per box for professional medical use.
- Defined Medical Device Purpose: Manufacturer documentation identifies temporary improvement of facial wrinkles as the intended purpose.
Composition & Specifications
| Product Name | REJURAN S |
|---|---|
| Brand | REJURAN |
| Manufacturer | PharmaResearch Co., Ltd. |
| Country of Origin | South Korea |
| Product Category | Polynucleotide (PN) Injectable Medical Device |
| Main Ingredient | Sodium Polynucleotide (PN) |
| PN Concentration | 20 mg/mL (2%) |
| Ingredient Origin | Purified Salmon-Derived DNA |
| Formulation | High-Viscosity PN Solution |
| Relative Viscosity | High (Compared with Standard REJURAN) |
| Volume per Syringe | 1 mL |
| Packaging | 1 mL × 1 Prefilled Syringe / Box |
| Manufacturer-Stated Intended Purpose | Temporary Improvement of Facial Wrinkles |
| Storage Temperature | 1–30°C (Protected from Light) |
How REJURAN S Works
REJURAN S contains polynucleotides, long-chain molecules composed of repeating nucleotide units derived from purified salmon DNA. Polynucleotides are hydrophilic polymers capable of interacting with water and contributing to the physical environment of the extracellular matrix.
Scientific research on PN-based medical materials has investigated their interactions with dermal fibroblasts, extracellular matrix components, tissue hydration, and skin elasticity. These mechanisms provide a scientific basis for studying PN in tissue-restoration applications, although findings from other PN formulations do not necessarily establish equivalent clinical outcomes for REJURAN S.
Compared with standard REJURAN, REJURAN S has a higher-viscosity formulation with reduced spreadability. This distinguishes its physical behavior within the REJURAN product range. Any clinical application, including treatment of localized skin depressions or scars, must be assessed against the approved indications and professional guidance applicable in the destination market.
What Makes REJURAN S Different?
REJURAN S belongs to PharmaResearch's polynucleotide-based REJURAN product family. Its distinguishing characteristic is formulation viscosity rather than the addition of a different primary active ingredient.
The manufacturer describes standard REJURAN as having medium viscosity, while REJURAN S has high viscosity and lower spreadability. These differences are relevant when healthcare professionals compare the physical characteristics of PN injectable products.
REJURAN S is frequently marketed for scar-focused aesthetic applications. However, PharmaResearch's published Korean product information identifies temporary improvement of facial wrinkles as its intended purpose. Marketing applications should not be interpreted as additional regulatory approvals.
Storage & Handling
- Storage Temperature: Store at room temperature between 1°C and 30°C.
- Light Protection: Keep the product protected from direct light.
- Freezing: Do not freeze.
- Professional Handling: Follow the instructions for use, package labeling, and applicable medical-device handling requirements.
Storage instructions, labeling, and permitted indications may vary by market. Always refer to the documentation accompanying the supplied product.
Frequently Asked Questions
What is the main ingredient in REJURAN S?
REJURAN S contains sodium polynucleotide (PN), a purified DNA-derived polymer obtained from salmon. The reported concentration is 20 mg/mL, equivalent to 2% w/v.
What is the difference between REJURAN S and standard REJURAN?
Both products belong to PharmaResearch's PN-based injectable medical device range. REJURAN S has higher viscosity and lower spreadability than standard REJURAN. REJURAN S is supplied in a 1 mL syringe, whereas standard REJURAN is commonly packaged as two 2 mL syringes per box.
Does REJURAN S contain hyaluronic acid or lidocaine?
PharmaResearch's published composition for REJURAN S identifies polynucleotide as its principal material and does not list hyaluronic acid or lidocaine. This differs from REJURAN HB Plus, which includes PN, hyaluronic acid, and lidocaine. Buyers should verify the ingredient declaration on the supplied product's market-specific label.
Is REJURAN S specifically approved for acne scar treatment?
REJURAN S is commonly associated with scar-focused aesthetic applications. However, PharmaResearch's published Korean product information states that its intended purpose is the temporary improvement of facial wrinkles. Approved indications may differ by jurisdiction and must be confirmed through the relevant local regulatory documentation.
Who should use REJURAN S?
REJURAN S is an injectable medical device intended for professional medical use. Patient suitability, product selection, and any clinical application must be determined by appropriately qualified healthcare professionals according to the applicable instructions for use and local regulations.