Kiara Reju

Product Overview

Kiara Reju is a South Korean PDRN skin booster manufactured by BioPlus Co., Ltd. The formulation combines sodium DNA, commonly described as polydeoxyribonucleotide (PDRN), with hyaluronic acid (HA) and niacinamide. Kiara Reju is developed for professional aesthetic skin-care applications, with ingredients associated with skin hydration, conditioning, and overall skin-quality support. The documented export presentation contains three pre-filled 2.2 mL syringes, providing a total of 6.6 mL per box.

The combination of PDRN, HA, and niacinamide distinguishes Kiara Reju from conventional hyaluronic acid-only skin boosters. Hyaluronic acid contributes water-binding properties, PDRN is associated with tissue-repair research, and niacinamide is widely studied for its role in skin barrier function and pigmentation-related pathways.

Kiara Reju is included in the BioPlus skin booster portfolio. Product classification and permitted application methods depend on the specific market version. The manufacturer's export brochure identifies the referenced presentation as a cosmetic product, while separate Korean medical device records also identify Kiara Reju among registered device models.

This TEOSQUARE product page provides composition, packaging, formulation characteristics, and regulatory information to help professional buyers evaluate the appropriate Kiara Reju presentation.

Key Features

• PDRN + HA + Niacinamide Complex: Combines sodium DNA, hyaluronic acid, and niacinamide in a multi-ingredient skin booster formulation.
• Hyaluronic Acid-Based Hydration: Contains HA, a hydrophilic glycosaminoglycan known for its ability to bind water and contribute to tissue hydration.
• PDRN-Associated Skin Conditioning: Includes sodium DNA, a polynucleotide-derived ingredient investigated for its biological interactions with tissue-repair and skin-conditioning pathways.
• Niacinamide-Enriched Formula: Incorporates niacinamide, a vitamin B3 derivative studied for its contribution to epidermal barrier function and skin-tone regulation.
• 2.2 mL Pre-Filled Syringes: The documented export package contains three 2.2 mL syringes, equivalent to 6.6 mL of product per box.

Composition & Specifications

Kiara Reju combines three principal skin-conditioning ingredients: hyaluronic acid, sodium DNA (PDRN), and niacinamide. The manufacturer's export brochure provides the complete ingredient declaration, while published distributor specifications report differing quantitative concentrations.

Full Ingredient List

The manufacturer's ingredient declaration for the Kiara Reju export formulation includes Water, Hyaluronic Acid, Niacinamide, Sodium Chloride, Disodium Phosphate, Sodium Phosphate, and Sodium DNA.

Understanding the Main Ingredients

Hyaluronic Acid (HA): A naturally occurring glycosaminoglycan with a strong affinity for water. HA contributes to the hydration and viscoelastic properties of the extracellular matrix and is widely used in cosmetic and medical aesthetic formulations.

Sodium DNA (PDRN): A DNA-derived polymer ingredient used in regenerative medicine research and selected aesthetic formulations. Experimental studies involving PDRN have examined cellular responses associated with tissue repair, inflammation, and extracellular matrix regulation.

Niacinamide: A water-soluble derivative of vitamin B3 that participates in cellular metabolism through its relationship with nicotinamide adenine dinucleotide (NAD). Niacinamide is also studied in dermatology for its effects on skin barrier function, pigmentation pathways, and epidermal conditioning.

Published commercial sources commonly report HA at 20 mg/mL and niacinamide at 1 mg/mL. However, PDRN concentrations are inconsistently reported, including values of 2 mg/mL and 5 mg/mL. These quantitative specifications should be verified against the supplied product's original manufacturer-issued documentation.

How Kiara Reju Works

Kiara Reju combines ingredients with distinct physicochemical and biological properties. Its formulation brings together the water-binding characteristics of hyaluronic acid, the tissue-repair research associated with PDRN, and the skin-conditioning properties of niacinamide.

Hyaluronic Acid and Skin Hydration

Hyaluronic acid is a major component of the extracellular matrix in human connective tissues. Its hydrophilic molecular structure allows it to associate with water, contributing to the hydration, lubrication, and mechanical properties of surrounding tissues.

In skin-care formulations, HA is valued for its moisture-retaining characteristics. Its performance depends on molecular characteristics, formulation, concentration, and method of application.

PDRN and Tissue-Repair Pathways

Polydeoxyribonucleotide consists of DNA-derived polymer fragments that have been investigated in experimental and clinical research involving tissue repair and regeneration.

Research involving certain PDRN preparations has described biological activity associated with adenosine A2A receptor signaling and nucleotide salvage pathways. These mechanisms have been investigated in relation to inflammatory regulation, cellular proliferation, and tissue remodeling.

Such findings provide a scientific background for PDRN-containing aesthetic products. However, the results of studies involving other PDRN preparations do not independently establish equivalent clinical effects for Kiara Reju.

Niacinamide and Skin Barrier Function

Niacinamide participates in cellular metabolic processes as a precursor of NAD-related coenzymes. These coenzymes are involved in numerous biochemical reactions associated with cellular energy metabolism and maintenance.

Dermatological studies have also investigated niacinamide for its effects on epidermal barrier function, pigmentation regulation, and skin appearance. Some evidence suggests that topical niacinamide can influence melanosome transfer and improve measures of skin barrier performance.

These findings primarily concern specific tested formulations and application methods. They should not be interpreted as direct proof of identical clinical outcomes from Kiara Reju.

Combined Formulation Concept

The Kiara Reju formulation combines ingredients associated with hydration, tissue conditioning, and cellular maintenance in one product. This multi-ingredient composition provides a basis for its positioning within the Korean skin booster market.

The presence of multiple biologically relevant ingredients does not by itself demonstrate synergistic efficacy. Product-specific clinical evidence is necessary to establish the magnitude, duration, and safety of any claimed treatment outcomes.

Packaging & Product Presentation

Kiara Reju is supplied in a pre-filled syringe presentation. The manufacturer's documented export packaging contains three syringes with a nominal volume of 2.2 mL each.

The 2.2 mL × 3 syringe format is the documented export presentation. Historical market documentation also references other Kiara Reju packaging configurations, but these should not be assumed to represent the same formulation, current availability, or regulatory classification.

The syringe presentation does not independently establish authorization for injection. Permitted application routes and professional-use requirements must be verified against the specific product classification and labeling in the destination market.

Storage & Handling

The BioPlus export brochure specifies room-temperature storage for Kiara Reju. An exact numerical temperature range is not provided in the referenced manufacturer product information.

• Storage Conditions: Store at room temperature in accordance with the original manufacturer labeling.
• Original Packaging: Keep the product in its supplied packaging until required for its permitted use.
• Environmental Protection: Avoid storage conditions that conflict with the temperature and environmental requirements printed on the product.
• Packaging Inspection: Check the syringe, container closure, and packaging for visible damage or contamination.
• Product Traceability: Verify the product name, manufacturing batch, expiration date, and market-specific labeling before use.

Exact temperature limits, shelf life, and handling requirements should be confirmed against the original supplied product. Do not assume that storage conditions for other BioPlus products apply to Kiara Reju.

Safety & Regulatory Considerations

Kiara Reju is marketed internationally as a PDRN-based aesthetic skin booster. However, product classification and permitted application methods require careful verification because regulatory documentation differs between market presentations.

The manufacturer's export brochure identifies the referenced Kiara Reju formulation as a cosmetic product. Separately, South Korean medical device records identify Kiara Reju among the models covered by a BioPlus tissue-repair device registration.

These records should not be treated as interchangeable evidence of authorization. A cosmetic product must not be presumed suitable or approved for injection simply because it is packaged in a syringe or shares a name with a registered medical device model.

The presence of HA, sodium DNA, or niacinamide does not guarantee safety or establish suitability for every skin type or treatment method. Individual ingredients may cause irritation, hypersensitivity, or other adverse reactions depending on exposure and formulation.

Where a specific injectable medical device presentation is legally authorized, its use must comply with the corresponding instructions for use, contraindications, and professional training requirements. Invasive aesthetic procedures carry additional risks that cannot be evaluated from ingredient information alone.

Regulatory approval in South Korea does not establish equivalent authorization in other countries. Buyers should confirm the exact product version, classification, intended use, and applicable registration documents before procurement.

This description is intended for professional product identification and comparison. It does not constitute treatment guidance, establish patient suitability, or authorize any application method beyond the product's applicable labeling.

Frequently Asked Questions